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. 2008 Jun 20;19(7):690–698. doi: 10.1089/hum.2008.035

Table 1.

Data Collection Schedule

Study day Test article administration Body weight/temperature Blood sample collectiona Viremia testing Immune parametersb Shedding CSF examinationc
−2     X        
1 X X X X X X  
5 X X X X   X  
9   X X X   X X
15   X X X      
22   X X X      
29   X X X X    
57   X X X X    
85   X X X X    
1 year   X X X X   X

Abbreviations: CEA, carcinoembryonic antigen; CSF, cerebrospinal fluid; MV, measles virus; QRT-PCR, quantitative real-time polymerase chain reaction.

a

Blood parameters: CEA, hematology, coagulation, and clinical chemistry.

b

Immune parameters: complement, immunoglobulins, and MV antibody titers.

c

CSF examination (spinal tap): cell count and differential, morphology review, CEA, total protein, glucose, RNA isolation for QRT-PCR analysis, Vero cell overlay, and anti-measles antibody levels.