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. Author manuscript; available in PMC: 2009 Oct 3.
Published in final edited form as: J Org Chem. 2008 Aug 29;73(19):7603–7610. doi: 10.1021/jo801273q

Table 4.

Synthesis of Substituted Carbazoles by Cyclization of Biaryl Amides

graphic file with name nihms110661t4.jpg
Entry Substrate Product R Yield
(%)a
1 graphic file with name nihms110661t5.jpg graphic file with name nihms110661t6.jpg Me 93
2 F 90
3 graphic file with name nihms110661t7.jpg graphic file with name nihms110661t8.jpg Me 92
4 F 94
5 CF3 88
6 graphic file with name nihms110661t9.jpg graphic file with name nihms110661t10.jpg OMe 81
7 F 78
8 CF3 81
9 graphic file with name nihms110661t11.jpg graphic file with name nihms110661t12.jpg 85
10 graphic file with name nihms110661t13.jpg graphic file with name nihms110661t14.jpg 88
a

Isolated yield after silica gel chromatography, average of two runs.