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. Author manuscript; available in PMC: 2010 Feb 20.
Published in final edited form as: Nature. 2009 Aug 20;460(7258):1021–1025. doi: 10.1038/nature08260

Figure 2. CA04 sensitivity to antiviral compounds in mice.

Figure 2

Mice were intranasally inoculated with 104 PFU (50 μl) of CA04, KUTK-4, or A/Kawasaki/UTK-23/08 (H1N1). At 1 h pi, mice were administered oseltamivir phosphate, zanamivir, CS-8958, T-705, or distilled water and PBS (control). Three mice per group were euthanized on days 3 and 6 pi and the virus titres in lungs were determined by plaque assays in MDCK cells. *, p<0.05, **, p<0.01.