Fig. 2.

Effect of acute s.c. pretreatment (−15 min) with the selective sigma-1 receptor (Sig-1R) antagonist NE-100 on 1-, 3-, and 24-h intake of 1.25% w/v sucrose solution (a), water (b), and food (c), relative to dark cycle onset in sP rats under continuous access (24 h) conditions (n=8). Data represent mean+SEM intake, normalized for body weight. *P< 0.05, **P<0.01 vs. vehicle-treated group (Dunnett’s test)