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Effect of acute s.c. pretreatment (−15 min) with the selective sigma-1 receptor (Sig-1R) antagonist NE-100 on 1-h alcohol intake in sP rats (n=7/group) after an imposed 7-day deprivation from ethanol. Data represent mean+SEM intake normalized for body weight. **P< 0.01 vs. non-deprived group, #P<0.05 vs. vehicle-treated deprived group (Student’s t tests)
