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. Author manuscript; available in PMC: 2009 Sep 22.
Published in final edited form as: Neuropsychopharmacology. 2006 Oct 4;32(5):1052–1068. doi: 10.1038/sj.npp.1301214

Figure 6.

Figure 6

Effect of bilateral injection of murine Ucn 3 into the ventromedial (VMN; n = 7), paraventricular nuclei of the hypothalamus (PVN; n = 8), or medial amygdala (MeA; n = 6) on the mean (+ SEM) average post-meal interval during the third–fourth post-injection hours (a) and on aspects of feeding bout microstructure (b–e) during the first 4 post-injection hours. Intra-VMH and PVN treatment prolonged the post-meal interval during the period of anorexia (a). No treatment altered the number of feeding bouts (b), but intra-VMH Ucn 3 infusion reduced the average bout size (c) and slowed the within-bout eating rate (d). Intra-PVN Ucn 3 infusion also slowed the within-bout eating rate and increased the serial irregularity of feeding within bouts, calculated as the entropy of the probability joint return map for feeding (e). Based on log-transformed frequency histogram analysis of inter-feeding and inter-drinking intervals, a feeding bout was defined as three or more feeding events in which consecutive feeding events were < 35 s apart. *p < 0.05 vs within-subjects vehicle treatment.