Table 3.

Effect of Site-Specific Murine Ucn 3 Infusions on Meal Microstructure of Male Rats

	Ventromedial nucleus of the hypothalamus (VMN)		Paraventricular nucleus of the hypothalamus (PVN)		Medial amygdala (MeA)
Microstructure parameter	1–2 h	3–4 h	1–2 h	3–4 h	1–2 h	3–4 h
Meal frequency, no. of meals
0 μg	3.1±0.6	2.4±0.2	2.4±0.4	2.5±0.5	1.8±0.3	3.0±0.3
0.1 μg	3.3±0.4	1.7±0.3**	2.6±0.3	1.5±0.4	3.0±0.3*	3.3±0.5
0.5 μg	3.6±0.3	1.9±0.3**	3.3±0.5	1.6±0.3	2.7±0.5	2.2±0.4
Average meal size
Food, g
0 μg	1.6±0.2	1.7±0.2	1.5±0.2	1.6±0.2	2.1±0.2	1.9±0.2
0.1 μg	1.5±0.2	1.6±0.3	1.3±0.2	1.5±0.2	1.5±0.2	1.7±0.2
0.5 μg	1.1±0.1	1.6±0.2	1.3±0.1	1.5±0.3	1.4±0.2*	2.3±0.5
Water, ml
0 μg	0.6±0.1	1.8±0.4	1.4±0.4	1.7±0.5	1.8±0.6	2.2±0.2
0.1 μg	1.0±0.5	0.9±0.4	0.4±0.1*	0.9±0.2	1.2±0.3	1.8±0.2
0.5 μg	0.9±0.5	1.6±0.5	1.2±0.3*	1.5±0.4	1.4±0.5	2.0±0.9
Within-meal ingestion rate
Eating, mg/s
0 μg	6.8±0.5	6.4±0.5	6.0±0.4	5.6±0.3	5.8±0.4	5.5±0.2
0.1 μg	6.3±0.6	6.2±0.5	5.0±0.5*	5.5±0.5	5.8±0.2	5.5±0.3
0.5 μg	5.9±0.6	6.4±0.5	4.4±0.4**	5.7±0.5	5.5±0.5	5.3±0.3
Drinking, μl/s
0 μg	14.3±2.5	13.0±2.7	8.3±2.5	10.5±2.4	7.2±3.7	7.0±1.5
0.1 μg	6.7±1.3	14.6±2.7	6.9±2.3	10.0±4.0	6.3±2.3	7.3±1.1
0.5 μg	11.5±4.8	13.2±2.9	8.0±1.7	7.3±0.9	8.2±2.1	7.5±0.9

Asterisks indicate significant differences from vehicle condition,

^*p < 0.05,

^**p < 0.01.