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. Author manuscript; available in PMC: 2009 Sep 22.
Published in final edited form as: Biochem Pharmacol. 2008 Jul 8;76(6):726–737. doi: 10.1016/j.bcp.2008.06.022

Figure 7.

Figure 7

Effect of CBD on the in vitro AFC response in wild type C57BL/6 and CB1-/-/CB2-/- splenocytes. Splenocytes (5 × 106 cells) from C57BL/6 or CB1-/-/CB2-/- were treated with CBD (1-20 μM) or THC (20 μM) for 30 min, followed by stimulation with sRBC for 5 days. Cells were then cultured and the AFC were enumerated as stated in Figure 1. The data are expressed as the mean AFC/106 viable cells ± SE of quadruplicate cultures for one representative experiment (A.) or % VH results for CBD from four experiments are pooled, with the exception of the 15 μM group, which represents a single experiment (B.). * or ** denotes values that are significantly different from the respective vehicle control at p < 0.05 or 0.01.