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Immunoreactivity of IL6 in the cerebral cortex of a representative 10-month-old anti-GM-CSF antibody-injected Tg2576 mouse and a representative PBS vehicle-injected Tg2576 mouse. (A) Increased immunoreactivity of IL6 in a PBS vehicle-injected Tg2576 mouse and (B) decreased immunoreactivity of IL6 in an anti-GM-CSF antibody-injected (25 µg) Tg2576 mouse. Sections were photographed at ×40 the original magnification.
