Skip to main content
. Author manuscript; available in PMC: 2009 Sep 22.
Published in final edited form as: Parasite Immunol. 2009 Apr;31(4):210–219. doi: 10.1111/j.1365-3024.2009.01095.x

Figure 3.

Figure 3

Recombinant IsSMase programs CD4 T cells responding to associated soluble antigen to develop the capacity to express IL-4. Adoptively transferred CFSE-labeled BALB/c HA-specific TCR transgenic CD4 T cells were recovered following adoptive transfer into BALB/c recipients that were simultaneously treated intradermally with soluble HA peptide and either SGE, IsSMase or PBS (Control or C). A, Representative CFSE-dilution histograms (left side, with the percentage of TCR transgenic CD4 T cells that have diluted CFSE-fluorescence shown) and B, quantitative data (mean ± SEM) corresponding to panel A. C, Representative IFN-γ vs IL-4 intracellular staining plots corresponding to the CFSE-divided TCR transgenic CD4 T cells in panel A. D, Quantitative analysis of intracellular IL-4 expression. N=4 to 6 for each group.