Table 1.
Wet weights of rat UGM alone, wild-type and PSMA-transgenic prostate tissue recombinants after 8, 16 and 24 weeks of kidney grafting in intact male nude host mice treated with testosterone and estradiol. There was no difference in wet weights of wild-type and PSMA-transgenic tissue recombinants. Wet weights of both tissue recombinants declined significantly with serial grafting.
rUGM only | Wild-type tissue recombinants | PSMA-transgenic tissue recombinants | |||
---|---|---|---|---|---|
8 weeks | 19.2 ± 4 mg (11) | 103.2 ± 5.2 mg (9) | ![]() |
90.2 ± 7.4 mg (20) | ![]() |
16 weeks | 30.4 ± 5.2 mg (7) | 70.8 ± 11.4 mg (10) | 59.6 ± 6.5 mg (26)+ | ||
24 weeks | 19.7 ± 3.9 mg (8) | 57.3 ± 8.3 mg (27)+ | 62.8 ± 8.7 mg (32)* |
Data are reported as mean ± SE (n)
denotes p<0.01
denotes p<0.05 by Student’s t-test.