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Experimental groups to examine the effect of tamoxifen on the progression towards concurrent mammary and ovarian cancer.
| Treatment Group | CONT | TAM | CARC | CARC+TAM |
|---|---|---|---|---|
| Ovarian treatment | Vehicle | Vehicle | DMBA | DMBA |
| Systemic treatment | Vehicle | Vehicle | E2 | E2 |
| Tamoxifen treatment | Vehicle | Tamoxifen | Vehicle | Tamoxifen |
CONT = vehicle-treated animals, TAM = tamoxifen-treated animals, and CARC = carcinogen-treated animals.
