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. Author manuscript; available in PMC: 2009 Nov 7.
Published in final edited form as: Circ Res. 2008 Nov 7;103(10):1058–1071. doi: 10.1161/CIRCRESAHA.108.180588

Table 2.

Commonly used cardiomyocyte markers and extracardiac tissues/cell types in which they can also be expressed.

Marker Extracardiac site(s) of expression
Nkx2.5 Embryo: Pharyngeal endoderm, spleen, stomach, tongue110, 111
GATA4 Adult: Ovary, testis, lung, liver, and small intestine112
Embryo: Proximal anddistal gut, testis, ovary, liver, visceral endoderm, and parietalendoderm112, 113
T-box 5 (Tbx5) Embryo: Eye, forelimb, genital papilla, lung, mandible, trachea114
Myocyte enhancer factor 2C (MEF2c) Adult: Skeletal muscle, brain, lymphocytes115, 116
Embryo: Skeletal muscle, smooth muscle, brain117, 118
Connexin-43 Ovary, testis, smooth muscle, eye, brain, macrophages, fibroblasts119, 120
Sarcomeric myosin heavy chain Skeletal muscle121
Sarcomeric actin Skeletal muscle122
Sarcomeric actinin Skeletal muscle123
Cardiac troponin I Fetal skeletal muscle124
Cardiac troponin T Fetal skeletal muscle125
Atrial natriuretic peptide Brain126
Smooth muscle α-actin Smooth muscle, myofibroblasts127
Desmin Smooth muscle, skeletal muscle128