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. 2009 Sep 2;8:38. doi: 10.1186/1476-511X-8-38

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Copyright © 2009 Zavvarreza et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effects of fatty acids (100 μM) and pharmacological PPARα and ACAT1 ligands on mRNA levels of PPARα in THP-1 macrophages derived foam cells. Cells were treated for 48 h with fatty acids and pharmacological compounds. mRNA levels analyzed by cyber green procedures. The values normalized to β-actin. All results represent means ± SD from triplicate determinations, representative of 3 independent experiments compared with control. Significant differences between treatments are indicated by one-way ANOVA followed by Tukey multicomparison test. *P ≤ 0.05.