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. 2009 Aug 27;10:269. doi: 10.1186/1471-2105-10-269

Table 6.

Type I error in the disease association study.

Disease model parameters SS* MB HB MDL GAB GPG GPF
DAF = 5% – 15%, GRR1 = 3 0.26 0.20 0.17 0.16 0.17 0.13 0.13
DAF = 5% – 15%, GRR1 = 5 0.32 0.24 0.21 0.20 0.22 0.16 0.17
DAF = 20% – 30%, GRR1 = 3 0.29 0.21 0.18 0.17 0.19 0.14 0.15
DAF = 20% – 30%, GRR1 = 5 0.34 0.25 0.22 0.22 0.23 0.17 0.19

Chi-square tests have been performed at 0.05 level of significance, on 250 sets of 50/50 case-control samples. Each entry depicts the proportion of blocks that have been falsely recognized as trait-associated to all the blocks that do not include the trait locus. * Method of single site test. See Table 1 for method abbreviations.