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. Author manuscript; available in PMC: 2010 Oct 2.
Published in final edited form as: Mutat Res. 2009 May 20;669(1-2):85–94. doi: 10.1016/j.mrfmmm.2009.05.004

Fig. 3.

Fig. 3

Fig. 3

(A) Confocal image of fluorescently-tagged oligonucleotide in and around the cell nucleus. HCT116-19 cells were electroporated with 8 μM of Cy3-labeled ODN (red) and allowed to recover for 24 hours. DAPI was used to label nucleus (blue). (B) Presence of ssODN stimulates H2AX activation. Confocal image of pH2AX in HCT116-19 cells in the presence of 8 μM 72NT. Camptothecin (CPT) (300 nM) treatment serves as positive control.