Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Jul 6;284(35):23491–23501. doi: 10.1074/jbc.M109.021899

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2009 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 1. — a, immunohistochemical localization of OPN in human kidney stone by light microscopy. Concentric layers/lamellae of organic matrix, rich in OPN, radiate from apparent nidi of calcification. b and c, at the ultrastructural level, colloidal-gold immunolabeling for OPN viewed by transmission electron microscopy shows OPN variably concentrated either at crystallite surfaces (b), here seen as voids after sample decalcification, or within the crystallites (within the void) and associated with a flocculent organic material evident after decalcification (c). d, scanning electron micrograph of COD crystals precipitated from normal male human urine by oxalate addition. Typical di-pyramidal COD crystals show prominent {101} crystallographic faces. e, Western blots for OPN of normal human urine (lane 1) and the protein extract of COD crystals precipitated from normal human urine (lane 2).