Table 1.
PLGA-based nanoparticle formulations prepared by means of dialysis method.
| Run | Polymer | Volume(b) | Surfcant | RA | Solvent |
|---|---|---|---|---|---|
| (mg/mL) | (L) | (mg/mL) | (mg/mL) | (% (a)DMSO) | |
| LG-1 | 2.5 | 3 | — | — | 100 |
| LG-2 | 2.5 | 2 | — | — | 100 |
| LG-3 | 2.5 | 1 | — | — | 100 |
| LG-4 | 1.4 | 1 | — | — | 100 |
| LG-5 | 1.0 | 1 | — | — | 100 |
| LG-6 | 1.4 | 1 | — | — | 70 |
| LG-7 | 1.4 | 1 | — | 0.7 | 70 |
| LG-8 | 1.5 | 1 | 0.4 | — | 85 |
| LG-9 | 1.5 | 1 | 0.5 | — | 84.5 |
| LG-10 | 1.5 | 1 | 0.5 | 0.7 | 84.5 |
| LG-11 | 1.5 | 1 | 0.7 | 0.7 | 84.5 |
| LG-12 | 1.5 | 1 | 0.4 | 0.6 | 85 |
| LG-13 | 1.6 | 1 | 0.4 | 0.6 | 81 |
(a)DMSO/H2O (% vol/vol).
(b)Volume of water in the outer compartment.