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. Author manuscript; available in PMC: 2009 Sep 23.

Published in final edited form as: Clin Chem. 2008 Dec 4;55(2):274–284. doi: 10.1373/clinchem.2008.115857

Effect of in vitro treatment with CRP on protein or mRNA concentrations in aortic tissues. Aortic segments excised from 2 month old rats were treated with CRP (50 mg/l) and SNAP (100 mg/l) as indicated for 6 hours. Protein concentrations of (A) AT₁, (B) AT₂, (C) ET_A and (D) eNOS are shown. The upper portion is a representative western blot of the protein of interest, while the lower graph is of the mean densitometric data of protein values normalized to β-actin. (E) ET-1 mRNA values are shown normalized to GAPDH. Data are presented as the mean ± SEM of three independent experiments. * P < 0.05 vs. control group; # P < 0.05 vs. CRP group. (AT₁: * P=0.002, #P=0.023 AT₂: * P=0.000, #P=0.002 ET_A: * P=0.003, #P=0.039 eNOS: * P=0.02, ET-1: * P=0.016, #P=0.003)

Effect of in vitro treatment with CRP on protein or mRNA concentrations in aortic tissues. Aortic segments excised from 2 month old rats were treated with CRP (50 mg/l) and SNAP (100 mg/l) as indicated for 6 hours. Protein concentrations of (A) AT₁, (B) AT₂, (C) ET_A and (D) eNOS are shown. The upper portion is a representative western blot of the protein of interest, while the lower graph is of the mean densitometric data of protein values normalized to β-actin. (E) ET-1 mRNA values are shown normalized to GAPDH. Data are presented as the mean ± SEM of three independent experiments. * P < 0.05 vs. control group; # P < 0.05 vs. CRP group. (AT₁: * P=0.002, #P=0.023 AT₂: * P=0.000, #P=0.002 ET_A: * P=0.003, #P=0.039 eNOS: * P=0.02, ET-1: * P=0.016, #P=0.003)