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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Biochimie. 2009 Jul 14;91(10):1307–1310. doi: 10.1016/j.biochi.2009.07.001

Figure 3.

Figure 3

The effect of c-Myc on the hypoxia (Hy) mediated decrease in the global levels of acetylated histone H4 (AcH4) Wild-type (c-Myc+/+) and c-Myc knockout (c-Myc−/−) Rat-1 cells were cultured under normoxic (N) or hypoxic (Hy: 1% O2) conditions for 24 hr. Total histones (5 μg per lane) were separated on 15% SDS-PAGE gels and then subjected to Western blotting with antibodies against AcH4. The lower panels show the gels stained with Coomassie Blue (after being transferred) in order to monitor for loading of the histones.