Skip to main content
. Author manuscript; available in PMC: 2010 Aug 28.
Published in final edited form as: Circ Res. 2009 Aug 28;105(5):406–407. doi: 10.1161/CIRCRESAHA.109.205203

Figure 1. Crosstalk between FGF and BMP Signaling Pathways during Proepicardial Differentiation.

Figure 1

Proepicardial cells, likely a heterogeneous population (as indicated by shading), differentiate down the cardiomyocyte lineage in response to BMP signaling or down a non-cardiomyocyte cardiac lineage in response to FGF signaling. Further, the FGF signaling pathway is dominant over the BMP pathway as FGF signaling through ERK can block BMP-induced cardiomyocyte differentiation.