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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Biomark Med. 2009 Aug 1;3(4):385–396. doi: 10.2217/BMM.09.33

Figure 3. Relevant colorectal cancer subnetworks and pathways.

Figure 3

(A) Protein interaction graph of the APC (center) axis. Nodes (n = 70) are indicated as glyphs (e.g., enzymes, transcription factors and receptors) and interactions with APC are indicated by lines. Evidence of the interactions is based on literature curation. The nominal cellular compartment of each protein is indicated by annotation on the right. (B) Map of the canonical WNT-signaling pathway, including APC (left, center). MetaCore©.