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. 2000 Oct 7;321(7265):860–864. doi: 10.1136/bmj.321.7265.860

Table 2.

Age adjusted bone mineral density (g/cm2) with 95% confidence intervals by exposure to fluoride in drinking water, 1971-90

Anatomical site No exposure Mixed exposure Continuous exposure P value
No exposure v mixed No exposure v continuous
Lumbar spine (n=6433) 0.857 (0.850 to 0.864) 0.850 (0.840 to 0.860) 0.866 (0.860 to 0.873) 0.262 0.045
Proximal femur (n=6420):
 Neck 0.651 (0.647 to 0.658) 0.650 (0.645 to 0.657) 0.661 (0.657 to 0.664) 0.871 0.002
 Trochanter 0.562 (0.558 to 0.566) 0.559 (0.553 to 0.564) 0.568 (0.565 to 0.572) 0.355 0.032
 Ward's triangle 0.432 (0.428 to 0.437) 0.431 (0.426 to 0.438) 0.437 (0.433 to 0.441) 0.915 0.104
 Intertrochanter 0.901 (0.895 to 0.908) 0.887 (0.879 to 0.896) 0.888 (0.882 to 0.894) 0.014 0.002
Distal radius (n=7067) 0.371 (0.367 to 0.374) 0.358 (0.354 to 0.363) 0.364 (0.361 to 0.367) <0.001 0.001
Proximal radius (n=7113) 0.647 (0.643 to 0.651) 0.631 (0.626 to 0.637) 0.636 (0.632 to 0.639) <0.001 <0.001
Calcaneus (n=7104) 0.413 (0.409 to 0.416) 0.401 (0.396 to 0.405) 0.409 (0.406 to 0.412) <0.001 0.105