TABLE 1.

Changes in Psychosocial, Psychiatric, and Substance-Related Impairment Among MA Dependent Adults at 3-year Follow-Up: Linear Mixed-Effects Models

	Depression Diagnosis		Time		Depression × Time
Scale	β	p	β	p	β	p
Brief symptom inventory (global)	0.38	<0.001	−0.11	<0.001	0.05	0.004
Depression	0.42	<0.001	−0.16	<0.001	0.09	0.001
Anxiety	0.43	<0.001	−0.12	<0.001	0.04	0.07
Hostility	0.44	<0.001	−0.09	<0.001	0.00	0.94
Interpersonal sensitivity	0.40	<0.001	−0.12	<0.001	0.07	0.002
Obsessive	0.42	<0.001	−0.13	<0.001	0.07	0.004
Paranoid ideation	0.50	<0.001	−0.12	<0.001	0.02	0.21
Phobic anxiety	0.29	<0.001	−0.08	<0.001	0.04	0.01
Psychoticism	0.38	<0.001	−0.12	<0.001	0.05	0.01
Somatization	0.30	<0.001	−0.07	<0.001	0.04	0.02
Addiction severity index
Psychiatric composite	0.05	0.02	−0.01	<0.001	0.02	<0.001
Medical composite	0.04	0.26	−0.00	0.29	0.01	0.17
Employment composite	−0.04	0.22	−0.02	<0.001	0.01	0.03
Alcohol composite	−0.00	0.78	−0.00	<0.001	0.01	0.05
Drug composite	−0.01	0.20	−0.03	<0.001	0.01	<0.001
Legal composite	−0.01	0.63	−0.04	<0.001	0.01	0.06
Family composite	0.03	0.18	−0.03	<0.001	0.00	0.65