Ktrans |
volume transfer constant between the blood plasma and the extravascular extracellular space (min−1) |
kep |
rate constant between the extravascular extracellular space and blood plasma (min−1) |
ve |
volume of the extravascular extracellular space per unit volume of tissue i.e. the volume fraction of |
|
the extravascular extracellular space (%) |
F |
flow of whole blood per unit mass of tissue (ml g−1 min−1) |
E |
initial extraction ratio |
P |
permeability of the vessel wall (cm min−1) |
S |
surface area per unit mass of tissue (cm2 g−1) |
P |
tissue density (g ml−1) |
n |
whole blood volume per unit volume of tissue |
MTT |
mean transit time |
λ |
tissue blood partition coefficient (ml/g) |
rCBV |
relative cerebral blood volume |
rCBF |
relative cerebral blood flow |
FWHM |
full-width half-maximum |