Fig. 2. The cvt17Δ strain is defective in autophagy.
A, log phase cultures grown in 1% yeast extract, 2% peptone, 2% glucose (YPD) were shifted to medium lacking nitrogen (SD-N). Viability was determined by plating aliquots on YPD plates. B, indicated strains were shifted to SD-N as in A, with aliquots taken at indicated times. Crude lysates were subjected to immunoblot analysis with anti-API antiserum.