Figure 5.

Robust perfect temperature compensation of the model described in Fig. 3a. Rate constants (Appendix) refer to 25°C with A_set = 1. (a) All activation energies are 50 kJ/mol and temperature is 5°C. (b) All activation energies are 50 kJ/mol and temperature is 100°C. Please note the much shorter timescale compared to panel a needed for the system to approach the same steady state. (c) Activation energies are as given in the Appendix. The system is initially at its steady state at 5°C. At 0.02 time units, the temperature is changed to 100°C showing perfect homeostasis only in A. (d) Activation energies as in panel c. The system is initially at its steady state at 100°C. At 40.0 time units the temperature is changed to 5°C showing perfect homeostasis only in A.