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Phase diagram for the Mg2+ and spermine concentrations. Phase I: DNA has a coil conformation in the aqueous phase. Phase II: DNA is adsorbed onto the membrane surface. Phase III: DNA has a highly compact conformation in the aqueous phase. The field surrounded with broken lines is the intermediate region, in which different states of DNA molecules (coil and compact, in the aqueous phase and on the membrane surface) coexist within a single droplet.
