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. 2009 Sep 7;9:76. doi: 10.1186/1472-6750-9-76

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Copyright © 2009 Kuystermans and Al-Rubeai; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A histogram of the cell cycle phases for cMycCHO versus CHO-K1 culture. cMycCHO is represented by the non-shaded cell cycle profile (blue profile line) while the CHO-K1 profile represented by a shaded area underneath the histogram. It can be seen that the percentage frequency of the G₁/G₀region in the 200 channel emission spectra decreases below CHO-K1 as the culture progresses while the S-phase (between 200 and 360 emission channel) and G₂/M (at ~360 emission channel) is consistently greater with culture time for cMycCHO.