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Overall survival of RNOP-09 patients as compared to historical control. Kaplan-Meier estimates of overall survival according to treatment group. The unadjusted hazard ratio for death among patients treated with PEG-Dox and prolonged administration of TMZ as compared with those treated in the EORTC26981/NCIC-CE.3 trial was 0.83 (CI: 0.60-1.16; p = 0.28).
