Table 2.
VBM studies of grey matter in dyslexia
| Study | Sample | Measure | Statistical analysis |
|---|---|---|---|
| 1. Brown et al. (2001) | Adults mean age 24 years | Density | Height threshold P < 0.05, corrected P < 0.05 for extent |
| 2. Brambati et al. (2004) | Family study aged 13–57 years | Volume | Small volume correction at P < 0.05, minimum cluster size 25 voxels |
| 3. Silani et al. (2005) | Adults mean ages 24–28 years | Volume | Small volume correction for regions of interest 10 mm spheres, whole brain P < 0.05 corrected |
| 4. Vinckenbosch et al. (2005) | Adults aged 17–30 years | Density | Corrected P < 0.01 for height and P < 0.05 extent |
| 5. Eckert et al. (2005) | Children mean age 11 years | Volume | P < 0.001 uncorrected for ROIs, P < 0.05 FWE corrected/P < 0.00001 for other regions |
| 6. Hoeft et al. (2007) | Children and adolescents mean age 14 yearsa | Volume | Whole brain corrected at P = 0.01 for height and extent |
| 7. Kronbichler et al. (2008) | Adolescents mean age 15 years | Volume | Whole brain P < 0.005 uncorrected and volume of interest corrected FDR < 0.05 |
| 8. Steinbrink et al. (2008) | Adults mean age 20 years | Volume | Whole brain P < 0.05 FDR corrected, cluster size >650 |
| 9. Pernet et al. (2009) | Adults mean age 27 years | Volume | Between group maps corrected for multiple comparisons P = 0.003, FDR correction q = 0.05 |
aThe study by Hoeft et al. (2007) used reading age and chronological age matched controls. Reading age matched controls had a mean chronological age of 9 years