Table 2. Significant Time Effects on Measures.
| Least Square Means (SE) at 3 Timepoints | ||||
|---|---|---|---|---|
| Measure | Baseline | 12 Months | 18 Months 1 | P2 |
| Total Recall | -.53 (.15) | -.18 (.15) | -.077 (.16) | .0048 |
| Compared to baseline | p=.0055 | p=.0016 | ||
| Long Term Storage | -.41 (.15) | -.22 (.15) | .0018 (.15) | .011 |
| Compared to baseline | p=.144 | p=.0028 | ||
| Significant Time Effects by Treatment | ||||
| Least Square Means (SE) at 3 Timepoints | ||||
| Measure | Baseline | 12 Months | 18 Months | P2 |
| SF-36, Mental Component Scale (MCS) | .034 | |||
| HSCT | 43.62 (2.32) | 49.40 (1.87) | 50.26 (1.78) | |
| Compared to baseline | p=.013 | p=.0097 | ||
| Other treatment | 48.16 (1.47) | 48.57 (1.61) | 49.64 (1.53) | |
| Compared to baseline | p=.69 | p=.21 | ||
| Significant Time Effects by Diagnosis | ||||
| Least Square Means (SE) at 3 Timepoints | ||||
| Measure | Baseline | 12 Months | 18 Months | P2 |
| Phonemic Fluency | .014 | |||
| CML | -.13 (.11) | .10 (.13) | .065 (.12) | |
| Compared to baseline | p=.009 | p=.033 | ||
| MDS | -.039 (.29) | -.47 (.20) | -.033 (.26) | |
| Compared to baseline | p=.16 | p=.98 | ||
| Pegboard, Dominant | .041 | |||
| CML | -.72 (.20) | -.55 (.16) | -.46 (.18) | |
| Compared to baseline | p=.38 | p=.094 | ||
| MDS | -.1.79 (.50) | -1.41 (.54) | -2.32 (.58) | |
| Compared to baseline | p=.46 | p=.092 | ||
1
The difference between the 18 and 12 month values were not statistically significant, with p>0.05.
2
P-values for the Total Recall and Long-Term Storage are for time effects across all patients. P-values for other outcomes are for the time-by-treatment or time-by diagnosis interaction.