Table 3. Selected Neuropsychological Measures.
| Baseline Mean (SD) |
12 months Mean (SD) |
18 months Mean (SD) |
Estimate (SE) | P-value1 | |
|---|---|---|---|---|---|
| TRAILS B | |||||
| CML | .37 (1.14) | .49 (.94) | .58 (.99) | .69 (.32) | .034 |
| MDS | -.36 (1.77) | -.33 (1.32) | -.074 (.90) | ||
| HSCT | .0069 (1.33) | .33 (.84) | .59 (.86) | -.11 (.21) | .60 |
| Other Tx | .422 (1.17) | .43 (1.10) | .48 (1.07) | ||
| TRAILS B | |||||
| CML | -.38 (2.53) | .069 (1.61) | .12 (1.66) | 2.09 (.53) | .0002 |
| MDS | -1.42 (2.46) | -2.20 (2.21) | -1.36 (2.33) | ||
| HSCT | -.40 (1.96) | -.48 (1.83) | -.16 (1.22) | -.57 (.35) | .11 |
| Other Tx | -.55 (2.80) | -.053 (1.82) | .048 (2.00) | ||
| PEGBOARD, Dominant | |||||
| CML | -.71 (1.73) | -.55 (1.45) | -.45 (1.65) | N/A2 | |
| MDS | -1.74 (1.36) | -1.41 (1.55) | -2.44 (1.74) | ||
| HSCT | -1.36 (2.20) | -1.32 (1.52) | -1.40 (1.99) | -1.13 (.31) | .0005 |
| Other Tx | -.57 (1.37) | -.31 (1.35) | -.23 (1.47) | ||
| PEGBOARD, non-Dominant | |||||
| CML | -.77 (1.69) | -.66 (1.52) | -.54 (1.66) | 1.47 (.50) | .0042 |
| MDS | -1.71 (1.42) | -1.86 (2.13) | -2.40 (2.24) | ||
| HSCT | -1.20 (2.21) | -1.46 (1.68) | -1.55 (1.99) | -1.08 (.33) | .0019 |
| Other Tx | -.70 (1.33) | -.45 (1.51) | -.27 (1.52) | ||
| SEMANTIC FLUENCY | |||||
| CML | .089 (1.02) | .21 (1.16) | .14 (1.11) | -.16 (.34) | .64 |
| MDS | .23 (.84) | .13 (1.12) | .79 (.62) | ||
| HSCT | -.038 (1.01) | .27 (1.08) | -.053 (.66) | -.21 (.23) | .36 |
| Other Tx | .18 (.99) | .16 (1.19) | .33 (1.26) | ||
1
P-values are for the main effects of diagnosis and treatment, across all time points.
2
Because of the significant time-by-diagnosis interaction shown in Table 2, the difference between patients with CML and MDS varies with time and cannot be reported as a single estimate.