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. Author manuscript; available in PMC: 2009 Sep 23.
Published in final edited form as: Mol Genet Genomics. 2008 Apr 23;280(1):25–39. doi: 10.1007/s00438-008-0342-5

Fig. 6.

Fig. 6

Disruption of SAL1 exacerbates the respiratory deficient and mtDNA instability phenotypes of shy1Δ and mtg1Δ mutants. (A) Growth phenotype of W303-1B (wt), CS415 (sal1Δ), BK37-1B (shy1Δ) and BK37-1C (sal1Δ shy1Δ) on YPD after 10 days at 30°. (B) Petite frequency in strains shown in (A) after 31 hrs of growth in YP supplemented with 10% glucose. The values represent the average of two independent experiments with average deviations. (C) A representative tetrad from BK38 (+/mtg1Δ, +/sal1Δ) dissected on YPD. (D) Southern-blot analysis of CfoI-digested total cellular DNA extracted from a complete tetrad grown in YPGal. Total mtDNA was used as probe. i.c. internal control for loading. ΔΔ, sal1Δ mtg1Δ mutant.