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Novel cytotoxic agents under investigation or approved for metastatic breast cancer
| Agent | Drug class | Stage of development in breast cancer |
| Nanoparticle albumin-bound (nab-) paclitaxel | Taxane | Approved |
| Larotaxel | Taxane | III |
| Ixabepilone | Epothilone | Approved |
| Patupilone | Epothilone | II |
| ZK-EPO | Epothilone | II |
| BMS-310705 | Epothilone | I |
| KOS-862 | Epothilone | Discontinued |
| Vinflunine | Vinca alkaloid | II |
| Eribulin | Mitotic inhibitor | III |
| Trabectedin | Nucleotide excision repair inhibitor, cell cycle inhibitor | III |
