Table 2.
Nonventilated Room air |
VT 6 ml/kg Room air |
VT 30 ml/kg Room air |
|
---|---|---|---|
PH | 7.41 ± 0.04 | 7.36 ± 0.03 | 7.32 ± 0.05 |
PaO2 (mm Hg) | 99.1 ± 0.4 | 82.6 ± 7.3 | 86.8 ± 1.2 |
PaCO2 (mm Hg) | 40.3 ± 0.4 | 42.1 ± 1.5 | 35.1 ± 1.7 |
MAP (mm Hg) | |||
Start | 87 ± 1.6 | 85.7 ± 2.6 | 84.2 ± 2.1 |
End | 85 ± 0.7 | 81.2 ± 1.9 | 73.6 ± 6.3 |
PIP, mm Hg | |||
Start | 9.7 ± 1.3 | 23.8 ± 2.5 | |
End | 11.8 ± 1.6 | 28.1 ± 3.4 |
Arterial blood gases and mean arterial pressure of normal nonventilated mice and mice ventilated at a tidal volume of 6 ml/kg or 30 ml/kg for 5 hours (n = 10 per group). VT = tidal volume; MAP = mean arterial pressure; PIP = peak inspiratory pressure.