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. 2009 Jul 6;13(4):R108. doi: 10.1186/cc7949

Table 2.

Physiological conditions at the beginning and end of ventilation

Nonventilated
Room air
VT 6 ml/kg
Room air
VT 30 ml/kg
Room air
PH 7.41 ± 0.04 7.36 ± 0.03 7.32 ± 0.05
PaO2 (mm Hg) 99.1 ± 0.4 82.6 ± 7.3 86.8 ± 1.2
PaCO2 (mm Hg) 40.3 ± 0.4 42.1 ± 1.5 35.1 ± 1.7
MAP (mm Hg)
 Start 87 ± 1.6 85.7 ± 2.6 84.2 ± 2.1
 End 85 ± 0.7 81.2 ± 1.9 73.6 ± 6.3
PIP, mm Hg
 Start 9.7 ± 1.3 23.8 ± 2.5
 End 11.8 ± 1.6 28.1 ± 3.4

Arterial blood gases and mean arterial pressure of normal nonventilated mice and mice ventilated at a tidal volume of 6 ml/kg or 30 ml/kg for 5 hours (n = 10 per group). VT = tidal volume; MAP = mean arterial pressure; PIP = peak inspiratory pressure.