TABLE 3.
Variables with possible influence on FTO mRNA expression in vastus lateralis muscle
| Estimate | 95% CI | Percent change | Effect of 1 SD | Percent change | P | |
|---|---|---|---|---|---|---|
| Basal FTO mRNA level | ||||||
| Age (elderly vs. young) | 0.72 | (0.64–0.82) | ↓28% | — | — | <0.0001 |
| Sex (men vs. women) | 1.27 | (1,12–1.43) | ↑27% | — | — | 0.002 |
| Zygosity (MZ vs. DZ) | 1.08 | (0.98–1.20) | ↑8% | — | — | 0.11 |
| Total fat (%) | 1.00 | (0.99–1.01) | — | 0.99 | ↓1% | 0.82 |
| Vo2max (ml · kg−1 · min−1) | 0.99 | (0.99–1.00) | ↓1% | 0.97 | ↓3% | 0.42 |
Model: ln FTO = adjusted for age, sex, zygosity, total fat percentages, and Vo2max. SD: adjusted for total fat percentage = 8.65, Vo2max = 9.62. P values are adjusted for twin pair and zygosity status.