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. 2009 Oct;58(10):2168–2174. doi: 10.2337/db09-0318

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© 2009 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 4. — Calculation of the systemic appearance of meal-derived glucose (A), EGP (B), and glucose disappearance (C) using the triple-tracer technique and a one-compartment model. Note that changing the estimates of the pool fraction (pV) has little effect on calculated rates. In contrast, using a dual-tracer approach, changing estimates of pV have marked effects on meal appearance (D), EGP (E), and glucose disappearance (F). Modified and reprinted with permission from Basu et al. Am J Physiol Endocrinol Metab 2003;284:E55–E69.