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. 2009 Jul 10;58(10):2386–2395. doi: 10.2337/db08-0617

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© 2009 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 7. — Cardiac function in Rac1-ko and wild-type mice after 8 weeks of STZ injection. Mouse hearts were isolated and perfused in a Langendorff system. Contractile function of heart was determined. Changes in the rate of contraction (+dF/dt_max, A) and relaxation (−dF/dt_min, B) are presented. Data are means ± SD, n = 5–12 per group. *P < 0.05 versus wild type in sham; #P < 0.05 versus wild type in STZ. WT, wild type.