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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Endocr Res. 2009;34(1-2):43–58. doi: 10.1080/07435800902913600

FIGURE 3.

FIGURE 3

Survival of sham, orx, and orx + E2 male mice after paraquat injection. Male mice (10 months old) were orchidectomized and implanted with E2 time-release pellets (0.001 mg/21 days) as described in the Experimental Procedures. Two weeks after orchidectomy and implantation with E2 pel-lets, the mice were treated with paraquat (75 mg/kg). The sham mice are shown as white circles, the orx mice as gray squares, and the orx + E2 mice as black diamonds. The survival of the mice was followed for 10 days and statistically analyzed using the Fleming-Harrington G-rho test as described in the Experimental Procedures. The number of animals in each group is given in Table 1.