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. Author manuscript; available in PMC: 2010 Jun 3.
Published in final edited form as: J Am Chem Soc. 2009 Jun 3;131(21):7327–7333. doi: 10.1021/ja809284s

Scheme 1.

Scheme 1

Production of the α-chloroacetamide-containing monomer (A). Pseudo first-order rate constants for the reactions of the monomers with 3-amino-1-propanol are given. Due to the 1000-fold rate difference, amines react selectively with the succinimidyl ester-containing monomer (B).