. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Mar 3;18(3):808–815. doi: 10.1158/1055-9965.EPI-08-0784

Table 2.

Cross-tabulation of grade and BMI categories in PCPT data and estimated relative risks

Cross-tabulation of grade and BMI categories in PCPT data
	BMI < 25		25 ≤ BMI < 30		BMI ≥ 30		Total
	N	(%)	N	(%)	N	(%)	Total

Cases
Low grade	213	(26.6)	420	(52.3)	169	(21.1)	802
High grade	23	(21.1)	49	(45.0)	37	(33.9)	109
Controls	2,376	(25.4)	4,789	(51.2)	2,182	(23.3)	9,347
Relative risks for overweight and obese men by arm and grade
	BMI < 25		25 ≤ BMI < 30		BMI ≥ 30

	Reference		RR (95% CI)		RR (95% CI)		P_trend

			P		P

All participants
Low grade	1.00		1.01 (0.86–1.18)		0.93 (0.76–1.13)
			0.92		0.45		0.47
High grade	1.00		1.13 (0.69–1.85)		2.00 (1.19–3.38)
			0.62		0.01		0.01
Placebo arm only
Low grade	1.00		0.96 (0.79–1.18)		0.89 (0.70–1.14)
			0.70		0.36		0.37
High grade	1.00		1.29 (0.59–2.80)		1.75 (0.74–4.15)
			0.53		0.20		0.20

NOTE: Low grade is defined as Gleason score 2–7 and high grade is defined as Gleason score 8–10. Relative risks are adjusted for age, race, family history of prostate cancer, diabetes status, and PCPT study arm.