Table 1.

Effect of MZ-2 on serum chemistry in ob/ob and lean mice. Results are presented as mean ± SD (n = 5 per group)

	Cholesterol (total) (mg/dl)	LDL (mg/dl)	HDL (mg/dl)	HDL/LDL	TG (mg/dl)	NEFA (mM/l)	Glucose (mg/dl)
ob/ob + wheel
Saline	207±14	19.8±3	92.4±6.6	4.67	90.6±20.9	2.02±0.4	432±108
MZ-2	246±48	17.6±2.9	119.7±12.8	6.80	90.2±15.1	2.06±0.4	412±97.6
ob/ob sedentary
Saline	248±33	21.4±5.1	122.2±12.6	5.71	130.5±25.5	3.02±0.6	649±35
MZ-2	258±20	22.3±1.7	130±12.4	5.84	122.3±45	2.7±0.8	447±89
Control + wheel
Saline	86±9.7	10±2.1	49±5.3	4.90	101.6±14.9	1.74±0.2	343.8±38.8
MZ-2	78±4.2	8.4±1.1	44.6±5.1	5.31	86.75±12.1	1.44±0.3	288.6±47.7
Control sedentary
Saline	86±7.7	8.4±1.5	47.4±3.6	5.64	89.4±13	1.2±0.2	262.6±31.7
MZ-2	81±6.7	9.7±2.1	44.4±5.6	4.58	62±7.9	0.92±0.2	266.7±23.1