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Transcriptional complexes associated with Myc. Depicted are individual coregulator complexes known to interact with Myc. In principle, several complexes could simultaneously associate with single Myc proteins. The binding of a Myc-Max heterodimer to the Miz-1 is shown, resulting in repression through inhibition of nucleophosmin (NPM). Many other protein interactions have been described for Myc (see the text).
