Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
mkp-1−/− and mkp-1+/+ mice lose equivalent amounts of bone in response to estrogen depletion. Eight-week-old mkp-1−/− and mkp-1+/+ mice were subjected to ovariectomy (OVX), sacrificed 6 weeks later, and compared with age-matched controls. Femurs were analyzed by micro-CT (A) and pQCT (B). Total density, trabecular bone density, cortical bone density, and cortical thickness are shown: black bar, control; white bar, OVX. Data are means ± SD; n = 8.
