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α-Catenin-expressing cells are preferentially located in well perfused regions of xenografts. DLD-1 xenograft section counterstained with propidium iodide to show nuclei (red; A), immunostained for α-catenin (green; B) and showing Hoechst fluorescence indicating region of perfusion (blue; C). D: Merging of three fluorescent channels. Cells lacking α-catenin expression located in nonperfused areas are indicated (white arrow). Scale bar = 25 μm.
