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Representative preneoplastic lesions as observed in H&E stained renal sections of OTA-treated rats apoptosis (white arrowheads) (A); karyomegally (white arrowheads) and cytoplasmic vacuolization (black arrowheads) in OTA-treated rats (B), peritubular fibrosis in OTA-treated rats (C), representative chronic progressive nephropathy observed in all treatment and control groups (D), bAT (E), and bAH (F).
