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. Author manuscript; available in PMC: 2009 Sep 24.
Published in final edited form as: Behav Pharmacol. 2008 Jul;19(4):298–307. doi: 10.1097/FBP.0b013e328308f1e6

FIGURE 2.

FIGURE 2

Effects of CP55940 and THC in beta-arrestin2+/+ and -/- mice. Mice were assayed before and at different times after i.p. injection of either 1.0 or 0.3 mg/kg CP55940 (left) or 10 mg/kg THC or vehicle (right) for latency to tail withdrawal (above) and rectal temperature (below). Change in rectal temperature and %Maximum Possible Effect (%MPE) were calculated as described under Methods. Data shown are mean ± SEM with n = 5 for each genotype for CP55940; n = 6-9 for THC, and n = 6 for for vehicle. *p < 0.05, ** p < 0.01, ***p < 0.001, at the times marked, for beta-arrestin2+/+ versus -/- by Bonferroni’s post-test.