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Effects of other cannabinoid agonists in beta-arrestin2+/+ and -/- mice. Mice were assayed before and at different times after i.p. injection of 50 and 250 mg/kg methanandamide (left) and 2.5 mg/kg O-1812 and 20 mg/kg JWH-015 (right) for latency to tail withdrawal (above) and rectal temperature (below). Data shown are mean ± SEM; n = 6 - 8 for each genotype for each drug.
