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Effect of CP55940 and vehicle (left) and THC (right) in the hot plate test of antinociception. %Maximum Possible Effect (%MPE) were calculated as described in Methods. Data shown are mean ± SEM with n = 5 for each group. *p < 0.05 at 90 min for beta-arrestin2+/+ versus -/- by Bonferroni’s posttest.
